ABSTRACT
The
data for this research work titled statistical analysis of reported cases of
Breast cancer was collected from the National Hospital Abuja. The statistical
tool used for the analysis of the data is Time Series. The time series model gave
a slope of -1.2 which indicates that new cases of the disease is gradually
decreasing.
CHAPTER ONE
1.0
INTRODUCTION
Breast
cancer (Malignant breast neoplasm) is cancer originating from the tissue most
commonly from the inner living of the milk ducts or the lobules that supply the
ducts with milk. According to one of the breast cancer journals (www.webmd.com)
the size, stage, rate of growth and other characteristics of the tumor
determine the series of treatment. Treatment may include surgery, drugs,
chromosomal therapy and (radiation and immunotherapy) surgical removal of the
tumor provides the benefits with surgery alone being capable of producing a
cause in long term disease free survival. Several chemotherapy regime are commonly in addition to surgery. Most forms
of thermotherapy kills cells that are dividing rapidly anywhere in the breast
that were missed by the surgery which usually extends survival somewhat,
although, radiation exposure to the heart may cause heart failure in the
future. Some breast cancers are sensitive to hormones such as estrogen and
progesterone which makes it possible to treat them blocking the effects of
these hormones.
1.1 BACKGROUND OF THE STUDY
Breast
cancer surgery in the 18th century, because of its visibility, breast cancer
was the form of cancer most often described in ancient documents, because
autopsies were rare, cancer of the internal
organ were essentially invisible to ancient medicine, breast cancer however
could be felt through the skin and in its advanced state often developed into
fumigating lesion, the junior would become necrotic (die from the inside
causing the tumor to appear to break up) and ulcerate through the skin, weeping
fetid dark fluid. The oldest description of cancer was discovered
in Egypt and dates back to approximately 1600BC. The Edwin Smith pangrus
described eight cases of tumors or ulcers of the breast that were treated by
cauterization, the writing says about the disease, there is no treatment for
centuries, physicians describes similar cases in their practices with the same
conclusion. Ancient, from the time of Greeks through the 17th century was based
on humoralism and thus believed that breast cancer was generally caused by
imbalances in the fundamental fluids of black biles, alternatively, patients
often saw it as divine punishment.
In
the 18th century, a wide variety of medical explanations were proposed,
including a black of sexual activity, physical injuries to the breast, curdled
breast milks and various forms of lymphatic blockages, either internal or due
to restrictive clothing. In the 19th century, Scottish surgeon John Rodman said
that there is a fear of cancer’s tendency to run in families. Although, breast
cancer was known in ancient times, it was uncommon until the 19th century when
improvements in sanitation and control of deadly infectious diseases result in
dramatic increase in life span. Previously, most women had died too young to
have developed breast cancer. Additionally, early and frequent child bearing
and breast feeding probably reduced the rate of breast cancer development in
these women who did survive to middle age. Ancient medicine believed that the
cause was systematic, rather than local and because surgery carried a high
mortality rate. The referred treatment tended to be pharmacological rather than
surgical. Breast cancer journal (www.webmd.com).
According
to society of women’s health research in the US (2005) both incidence and death
rates for breast cancer have been divining in the last few years in native
Americans and Alaskan, the research also indicated that breast cancer remains the most feared disease even though
heart disease is exaggerated than the risk of breast cancer. According to
“world cancer report 2008”, breast cancer caused 455,503 deaths worldwide
(13.7% of cancer deaths in women) breast cancer is more than 100 times common
in women than in men, although, males tend to have poorer outcome due to delay
in diagnosis.
The Federal
Capital Territory like other states in Nigeria had suffered great pain from
this deadly disease even before the establishment of National Hospital Abuja on
the 22nd of May 1999 by the federal government of Nigeria and was commissioned
by the former head of state, his Excellency, Gen. Abdulsalami Abubakar and
opened its door to patients on the 11th Oct. 1999.
1.2 STATEMENT OF THE PROBLEM
Breast cancer
is one of the dangerous disease that affect women in the world, causing pains
in the faces of our mother and even men in the society at large. This has
prompted the researcher to determine whether the reported cases of breast
cancer are on the increase or decrease within the period of ten years.
1.3 AIM AND OBJECTIVES OF THE STUDY
The aim of
this study is to analyze whether the rate of breast cancer is on the increase
or decrease within a period of ten years.
The objectives
of this research work are:
i.
To
determine the trend movement of the disease.
ii.
To
forecast the trend of the disease.
iii.
To
determine if the proportion of survival is equal among the specified age
groups.
1.4 SIGNIFICANCE OF THE STUDY.
This research
work will be useful to the Government, the medical centers, private and public
health practitioners, researchers who may like to investigate more about the
disease and to the society at large.
1.5 DELIMITATION OF THE STUDY.
This research
work covers a period of ten years and was restricted to National Hospital
Abuja.
1.6 LIMITATION OF THE STUDY.
Due to the
financial constraints and time factor, the researcher was unable to cover the
whole health center in Abuja to collect data for this research work. Therefore,
the researcher limited her findings to national hospital Abuja.
1.7 RESEARCH QUESTIONS.
The
researcher wants to impact more knowledge on breast cancer and to do this, the
following questions are stated below:
What are the
causes of breast cancer?
Can breast
cancer be prevented or controlled?
1.8 STATEMENT OF HYPOTHESIS.
HO: The rate
of breast cancer is on the decrease
HI: The rate
of breast cancer is not on the decrease.
1.9 DEFINITION OF TERMS.
Malignant
Tumor: A mass of cells growing on part of the body where they usually cause
medical problems.
Cancer: A
serious disease in which there is an abnormal growth in the body cell and kill
the normal body cells.
TOPIC: STATISTICAL ANALYSIS OF REPORTED CASES OF BREAST CANCER
Format: MS Word
Chapters: 1 - 5
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Delivery: Email
Number of Pages: 65
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