Introduction
Breast
cancer is the commonest site specific, malignancy affecting women and the most
common cause of cancer mortality in women world wide. Our knowledge about breast
cancer is evolving but it is still limited with respect to its etiology and
biology and with respect to its features in individual countries and cultures.
The study was conducted to identify and determine the risk factors for breast
cancer in a Tertiary hospital in Nigeria. A retrospective case control study
was carried out in National Hospital Abuja. A total of 544samples were used in
the work comprising of 272 cases and 272 controls . The data was obtained
directly from patients case file. Information obtained were; Sex, Occupation,
Weight, Height, Parity, Age, Religion, Marital Status, Smoking, Family history
of breast cancer, Alcohol consumption, Menarche and Oral Contraceptive history.
The data was entered and analyzed using SPSS 15 version. The P value accepted
as significant was set at P < 0 .05 at 95% confidence level. Test statistics
performed were chi-square (x2) and odds ratio (OR) in order to obtain the
association as well as level of risk of a given risk factor. Females
constituted 521 (95.8%) of the study population while males were 23(4.2%).
Patients age ranged between 25-74 years with age groups 35-44 and 45-54 years
constituting the highest frequencies of 158 (29.4%) and 160 (29.8%)
respectively. Those who had early menarche were 257(51.1%) while normal
menarche were 246 (48.9%). Population of women who used oral contraceptives
were 110 (21.8%) while those who did not use were 395 (78.2%). Parity among
patients ranged between 0-10 children with those having 1-5 children having the
highest frequency of 361 (72.8%). 264 (49.1%) of the patients consumed alcohol
while 274 (50.9%) did not consume alcohol. Mother 60 (40.0%) and Sister 37
(24.7%) had the highest frequency for patient with family history. Civil
servant 229 (43.5%) had the highest frequency for occupation of patients in the
study. This was followed by those doing business 120 (22.8%). Housewives 96
(18.3%) Retiree 49 (9.3%) Student 18 (3.4%) and Farmers 14 (2.7%). 25 (4.6) of
the patients smoked while 515 (95.4%) did not smoke. 47 (32.2%) of the patient
were underweight while 99 (67.8%) were over weight. 459 (84.7%) of patients
were Christians while 83 (15.3%) were practicing Islam. Finally 447 (82.9%)
were married while 56(10.4%) were single and widows were 36 (6.7%) in the
study. In conclusion, Gender, Age, Parity, Early menarche, Use of oral
contraceptives, Alcohol consumption, Occupation and family history of patients
with breast cancer were identified as risk factors for breast cancer as well as
had significant association for development of breast cancer. Smoking,
Religion, Marital status and BMI of patients were not identified as risk
factors for developing breast cancer in the study.
TOPIC: RISK FACTORS FOR BREAST CANCER IN A TERTIARY HOSPITAL IN ABUJA
Format: MS Word
Chapters: 1 - 5
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Delivery: Email
Number of Pages: 70
Price: 3000 NGN
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